Latest Clinical Publications

Cytokine-induced killer cells

CIK Autologous natural killer cells – NK cells have a therapeutic effect on advanced PCA patients

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Dendritic Cell therapy

Dendritic Cell Vaccination Enhances Immune Responses and Induces Regression of HER2pos DCIS Independent of Route_ Results of Randomized Selection Design Trial

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Ozone

Ozone Therapy for Tumor Oxygenation: a Pilot Study

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Specifically, O3 therapy induces moderate oxidative stress when interacting with lipids. This interaction increases endogenous production of antioxidants, local perfusion, and oxygen delivery, as well as enhances immune responses.

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DC/CIK therapy combinations with radiotherapy and chemotherapy

Co-culture of dendritic cells and cytokineinduced killer cells effectively suppresses liver cancer stem cell growth by inhibiting pathways in the immune system

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DLP+CIK Remarkable pathologic change in advanced prostate cancer patient using DLP_CIK combined therapy_ case report

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Oncolytic Virotherapy

ECHO-7 oncolytic virus in an adjuvant setting for stage I uveal melanoma; A retrospective case report.

Uveal melanoma is considered a rare disease, arising from choroidal melanocytes, iris or ciliary body. The disease ultimately leads to development of metastases in almost 50% of patients.

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Combination treatment with nivolumab and Rigvir of a progressive stage IIC skin melanoma patient

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A Case of Stage IV Chromophobe Renal Cell Carcinoma Treated with the Oncolytic ECHO-7 Virus, Rigvir®

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Effect of the oncolytic ECHO-7 virus Rigvir® on the viability of cell lines of human origin in vitro

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Long-term treatment with the oncolytic ECHO-7 virus of a melanoma stage IV M1c patient, a small lung cancer stage IIIA patient, and a histiocytic sarcoma stage IV patient-three case reports

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Multimodality Treatment of a Colorectal Cancer Stage IV Patient with FOLFOX-4, Bevacizumab, Rigvir Oncolytic Virus, and Surgery

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Oncolytic viruses are a fast-developing cancer treatment field. Numerous viruses have been tested in clinical trials and three are approved. The first, Rigvir®, is an immunomodulator with anti-tumour effect

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Melanoma Unknown Primary Brain Metastasis Treatment with ECHO-7 Oncolytic Virus Rigvir: A Case Report

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DLP+CIK Randomized controlled phase III trial of adjuvant chemo-immunotherapy with activated killer T cells and dendritic cells in patients with resected primary lung cancer

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Treatment of advanced pancreatic cancer
with combined DC-CIK infusions and S-1 was safe, resulted
in favorable PFS and OS, and modulated the peripheral blood
immune repertoire

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DLP+CIK Prospective study of cyclophosphamide, thiotepa, carboplatin combined with adoptive DC-CIK for triple negative metastatic breast cancers patients

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DLP+CIK A prospective study of the efficacy of a combination of autologous DCs and CIKs and chemotherapy in advanced non-small cell lung cancer patients

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DLP+CIK A clinical study evaluating dendritic and cytokine-induced killer cells combined with concurrent radiochemotherapy for stage IIIB non_small cell lung cancer

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The study confirms the efficiency and safety of the combination of DCs/CIKs cytotherapy with the thoracic radiotherapy for patients with locally advanced or metastatic non-small cell lung cancer

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DLP+CIK 2003-2013_Autologous tumor lysate-pulsed dendritic cell immunotherapy with cytokine-induced killer cells improves survival in stage IV breast cancer

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