1. Cytokine induced killer (CIK) cells have, as a key feature, a double T-cell and NK (Natural killer) cell-like phenotype. This unique combination of T-cell and NK-cell capabilities exerts a potent and widely MHC-unrestricted anti-tumor cytotoxicity against a broad range of cancer cells. What this means is that unlike other immune cells (eg T-Lymphocyte) which can only kill infected and malignant cells that have ‘red flags’ (such as MHC and antibodies) on them, CIK has the ability to identify and kill infected and cancer cells with or without these ‘red flags’. This factor potentiates a quick and an unbiased response by the immune system.
2. CIKs, alone or in combination with other therapies, have proven safe and efficient in clinical practice
3. CIK cells displayed a high cytotoxic potential against a broad range of varying tumor entities. CIK cell treatment has been proven to completely remit tumor burden, prolong survival durations and improve quality of life, even in advanced disease stages.