Dendritic Cell Immunotherapy

Immunotherapy treatments are changing the landscape of how we think about fighting advanced disease.

We offer here at Amber Life Cancer Clinic Dendritic Cell Vaccine (DCV) therapy and this is one of the groundbreaking clinical cancer treatments are being highlighted among the medical community.  Let us explain how and why we offer DCV in our clinic.

Dendritic Cell Therapy boosts the numbers by taking some immature Dendritic Cells from the patient’s own blood and cultivating, processing and activating them in the laboratory. It is a complex and highly specialized process that only a few laboratories can perform. AmberLife Cancer Clinic collaborates with a laboratory in Lithuania to assure the very best quality of cells.

How does the DCV affect cancer cells?

  1. The impact of DCV on tumor cells is not direct but based on the reprogramming of the antitumor immune response, which is a complicated multistage process.
  2. Dendritic cells are a type of immune cells that play very important role in starting the immune response – circulating in the blood as monocytes they are the first to come into contact with a presentable antigen, becoming activated into mature dendritic cells and then migrating to the lymph nodes, where they interact with other elements of the immune system.
  3. Monocytes are isolated from the patient’s blood, then a mixture of tumor-derived peptide antigens is added to the cell culture in the lab. After this maturation dendritic cells are now presenting specific tumor antigens on their surface and, when reintroduced back into patient’s blood, they trigger other types of immune cells – the T and B cells – to destroy the cancer cells specifically.

Why do patients choose DCV?

Dendritic Cell Therapy is a powerful form of immunotherapy used to fight cancer. The dendritic cell is the most potent of all antigen-presenting immune cells.

Their job is to break down cancer cells so the T-cells can then identify and attack them. Dendritic Cells are seldom active in adequate numbers to get this immune response in the face of active cancer.

This type of Dendritic Cell Therapy is targeted therapy. The particular tumor markers are cultured as well as trained, and therefore are tumor specific. This is a more advanced procedure than just training the Dendritic Cells.

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